ANU54932.1 protein (Hungateiclostridiaceae bacterium KB18)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

ANU54932.1

Glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)

Predicted Functional Partners:

ANU53776.1

0.570

ANU53856.1

0.462

ANU54725.2

0.458

ANU54745.1

0.442

ANU53299.1

0.406

Your Current Organism:

Hungateiclostridiaceae bacterium KB18

NCBI taxonomy Id: 1834198
Other names: H. bacterium KB18, Ruminiclostridium sp. KB18

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANU53299.1	ANU54745.1	A4V00_04220	A4V00_12365	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.622
ANU53299.1	ANU54932.1	A4V00_04220	A4V00_13395	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.406
ANU53776.1	ANU54932.1	A4V00_06880	A4V00_13395	2-dehydro-3-deoxyphosphogluconate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.570
ANU53856.1	ANU54932.1	A4V00_07320	A4V00_13395	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.462
ANU54725.2	ANU54932.1	A4V00_12265	A4V00_13395	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.458
ANU54745.1	ANU53299.1	A4V00_12365	A4V00_04220	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.622
ANU54745.1	ANU54932.1	A4V00_12365	A4V00_13395	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.442
ANU54932.1	ANU53299.1	A4V00_13395	A4V00_04220	Glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.406
ANU54932.1	ANU53776.1	A4V00_13395	A4V00_06880	Glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-dehydro-3-deoxyphosphogluconate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.570
ANU54932.1	ANU53856.1	A4V00_13395	A4V00_07320	Glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.462
ANU54932.1	ANU54725.2	A4V00_13395	A4V00_12265	Glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.458
ANU54932.1	ANU54745.1	A4V00_13395	A4V00_12365	Glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.442

Network Stats

number of nodes:

11

number of edges:

52

average node degree:

9.45

avg. local clustering coefficient:

0.952

expected number of edges:

12

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006189

De novo IMP biosynthetic process

11 of 15

2.33

8.92

7.99e-22

GO:0009113

Purine nucleobase biosynthetic process

2 of 3

2.29

1.42

0.0022

GO:0006541

Glutamine metabolic process

2 of 16

1.57

0.75

0.0292

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0034023

5-(carboxyamino)imidazole ribonucleotide mutase activity

3 of 3

2.47

1.86

0.00034

GO:0016879

Ligase activity, forming carbon-nitrogen bonds

4 of 39

1.48

1.13

0.0025

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005829

Cytosol

5 of 215

0.84

0.45

0.0478

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:552

De novo IMP biosynthetic process

9 of 11

2.38

7.64

1.52e-17

CL:549

Purine nucleoside monophosphate biosynthetic process

11 of 24

2.13

7.4

2.88e-20

CL:555

De novo IMP biosynthetic process

5 of 5

2.47

4.26

4.66e-09

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00230

Purine metabolism

11 of 95

1.53

3.38

2.94e-15

map01110

Biosynthesis of secondary metabolites

11 of 378

0.93

1.11

3.54e-09

map01100

Metabolic pathways

11 of 1142

0.45

0.39

0.00040

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005829

Cytosol

9 of 334

0.9

0.89

1.98e-05

GOCC:0005737

Cytoplasm

11 of 738

0.64

0.58

1.98e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0658

Purine biosynthesis

9 of 16

2.22

6.69

1.93e-16

KW-0436

Ligase

4 of 63

1.27

0.92

0.0047

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01001

AIR carboxylase

3 of 3

2.47

2.25

5.90e-05

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