STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDE83_004561Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (344 aa)    
Predicted Functional Partners:
DDE83_007892
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
DDE83_000068
2-oxoglutarate dehydrogenase, E1 component.
  
 0.981
DDE83_000752
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  
 0.974
DDE83_002400
Dihydrolipoamide succinyltransferase.
  
 0.952
DDE83_003938
ATP-citrate synthase (ATP-citrate (Pro-S-)-lyase).
  
0.947
DDE83_003937
ATP-citrate synthase (ATP-citrate (Pro-S-)-lyase).
 
 0.947
DDE83_000458
Mitochondrial succinate dehydrogenase cytochrome b560 subunit C.
  
 
 0.943
DDE83_001242
Pyruvate dehydrogenase protein x component.
  
 0.922
DDE83_000993
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  
 0.919
DDE83_000295
Succinate dehydrogenase.
  
 0.919
Your Current Organism:
Stemphylium lycopersici
NCBI taxonomy Id: 183478
Other names: CBS 116585 [[Stemphylium xanthosomatis]], CBS 120325 [[Stemphylium sophorae]], CBS 120326 [[Stemphylium oblongum]], CBS 122639, CBS 122803 [[Stemphylium pyrina]], CBS 124980 [[Stemphylium pruni]], CBS 124981 [[Stemphylium plantaginis]], IMI 98083 [[Stemphylium xanthosomatis]], S. lycopersici, Stemphylium oblongum, Stemphylium oblongum Yong Wang bis & X.G. Zhang, 2009, Stemphylium plantaginis, Stemphylium plantaginis Yong Wang bis & X.G. Zhang, 2006, Stemphylium pruni, Stemphylium pruni Yong Wang bis & X.G. Zhang, 2006, Stemphylium pyrina, Stemphylium pyrina Yong Wang bis & X.G. Zhang, 2009, Stemphylium sophorae, Stemphylium sophorae Yong Wang bis & X.G. Zhang, 2009, Stemphylium xanthosomae, Stemphylium xanthosomatis
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