Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
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Neighborhood
Groups of genes that are frequently observed in each other's genomic neighborhood.
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Textmining
Automated, unsupervised textmining - searching for proteins that are frequently mentioned together.
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Fusion
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDE83_002052
Flavoprotein oxygenase. (295 aa)
Predicted Functional Partners:
DDE83_008221
Geranylgerany transferase type ii beta subunit.
0.452
Your Current Organism:
Stemphylium lycopersici
NCBI taxonomy Id: 183478 Other names: CBS 116585 [[Stemphylium xanthosomatis]], CBS 120325 [[Stemphylium sophorae]], CBS 120326 [[Stemphylium oblongum]], CBS 122639, CBS 122803 [[Stemphylium pyrina]], CBS 124980 [[Stemphylium pruni]], CBS 124981 [[Stemphylium plantaginis]], IMI 98083 [[Stemphylium xanthosomatis]], S. lycopersici, Stemphylium oblongum, Stemphylium oblongum Yong Wang bis & X.G. Zhang, 2009, Stemphylium plantaginis, Stemphylium plantaginis Yong Wang bis & X.G. Zhang, 2006, Stemphylium pruni, Stemphylium pruni Yong Wang bis & X.G. Zhang, 2006, Stemphylium pyrina, Stemphylium pyrina Yong Wang bis & X.G. Zhang, 2009, Stemphylium sophorae, Stemphylium sophorae Yong Wang bis & X.G. Zhang, 2009, Stemphylium xanthosomae, Stemphylium xanthosomatis