STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDE83_001191Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (138 aa)    
Predicted Functional Partners:
DDE83_007537
Snf5-domain-containing protein.
    
  0.997
DDE83_002401
Histone H2A; Belongs to the histone H2A family.
 
 0.983
DDE83_002402
Histone H2B; Belongs to the histone H2B family.
 
 0.976
DDE83_006420
WD40 repeat-like protein.
    
 0.944
DDE83_002329
Histone H2A; Belongs to the histone H2A family.
 
 
 0.936
DDE83_005239
Histone H3; Belongs to the histone H3 family.
 
 
 0.912
GET3
ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]
    
 0.903
DDE83_004580
Histone H3.
 
 
 0.903
DDE83_004173
WD40 repeat-like protein.
    
 0.887
DDE83_003842
Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
    
 
 0.874
Your Current Organism:
Stemphylium lycopersici
NCBI taxonomy Id: 183478
Other names: CBS 116585 [[Stemphylium xanthosomatis]], CBS 120325 [[Stemphylium sophorae]], CBS 120326 [[Stemphylium oblongum]], CBS 122639, CBS 122803 [[Stemphylium pyrina]], CBS 124980 [[Stemphylium pruni]], CBS 124981 [[Stemphylium plantaginis]], IMI 98083 [[Stemphylium xanthosomatis]], S. lycopersici, Stemphylium oblongum, Stemphylium oblongum Yong Wang bis & X.G. Zhang, 2009, Stemphylium plantaginis, Stemphylium plantaginis Yong Wang bis & X.G. Zhang, 2006, Stemphylium pruni, Stemphylium pruni Yong Wang bis & X.G. Zhang, 2006, Stemphylium pyrina, Stemphylium pyrina Yong Wang bis & X.G. Zhang, 2009, Stemphylium sophorae, Stemphylium sophorae Yong Wang bis & X.G. Zhang, 2009, Stemphylium xanthosomae, Stemphylium xanthosomatis
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