Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KIH99871.1Metal-dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)    
Predicted Functional Partners:
KIH97037.1
Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.653
KIH97955.1
Nucleotide pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.587
KII00356.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.572
KII00598.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.560
KII00595.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LOG family.
     
  0.559
KIH99475.1
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.559
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
     
  0.559
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
     
  0.559
pyrR
Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
  0.559
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.559
Your Current Organism:
Streptomonospora alba
NCBI taxonomy Id: 183763
Other names: CCTCC AA 001013, DSM 44588, JCM 12680, S. alba, Streptimonospora albus, Streptomonospora alba Li et al. 2003, Streptomonospora albus, YIM 90003
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.