STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIH98860.1RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (952 aa)    
Predicted Functional Partners:
KII00618.1
GTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.661
rbpA-2
Membrane protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
 
    0.659
cobB-2
Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
   
    0.611
era
GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
   
    0.582
KII00368.1
3'-5' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.581
whiB-4
WhiB family transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.568
arc
ATPase AAA; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
 
     0.543
KIH98681.1
rRNA cytosine-C5-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
     0.514
KIH98879.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.494
KIH99448.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.486
Your Current Organism:
Streptomonospora alba
NCBI taxonomy Id: 183763
Other names: CCTCC AA 001013, DSM 44588, JCM 12680, S. alba, Streptimonospora albus, Streptomonospora alba Li et al. 2003, Streptomonospora albus, YIM 90003
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