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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIH98153.1Peptidase M48; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)    
Predicted Functional Partners:
KIH97194.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.603
KIH97193.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.596
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
       0.590
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
     
 0.568
grpE
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
 
  
 0.559
KIH99818.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.538
KIH99735.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.528
KIH98449.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.475
KIH98155.1
Phosphoglycerate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.466
KIH97042.1
Chemotaxis protein CheA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.458
Your Current Organism:
Streptomonospora alba
NCBI taxonomy Id: 183763
Other names: CCTCC AA 001013, DSM 44588, JCM 12680, S. alba, Streptimonospora albus, Streptomonospora alba Li et al. 2003, Streptomonospora albus, YIM 90003
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