node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KIH97257.1 | KIH97331.1 | LP52_19985 | LP52_19700 | Nitrilase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.886 |
KIH97257.1 | KIH98166.1 | LP52_19985 | LP52_14640 | Nitrilase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.759 |
KIH97257.1 | KIH98339.1 | LP52_19985 | LP52_13715 | Nitrilase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.819 |
KIH97257.1 | KII00414.1 | LP52_19985 | LP52_00840 | Nitrilase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.752 |
KIH97257.1 | guaA | LP52_19985 | LP52_25235 | Nitrilase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.496 |
KIH97331.1 | KIH97257.1 | LP52_19700 | LP52_19985 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nitrilase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.886 |
KIH97331.1 | KIH98166.1 | LP52_19700 | LP52_14640 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.802 |
KIH97331.1 | KIH98339.1 | LP52_19700 | LP52_13715 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.999 |
KIH97331.1 | KIH99296.1 | LP52_19700 | LP52_07925 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.957 |
KIH97331.1 | dapF | LP52_19700 | LP52_12785 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.975 |
KIH97331.1 | guaA | LP52_19700 | LP52_25235 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.968 |
KIH97331.1 | guaB | LP52_19700 | LP52_00790 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.962 |
KIH97331.1 | murD | LP52_19700 | LP52_11900 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.572 |
KIH97331.1 | topA | LP52_19700 | LP52_18640 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.788 |
KIH98166.1 | KIH97257.1 | LP52_14640 | LP52_19985 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Nitrilase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.759 |
KIH98166.1 | KIH97331.1 | LP52_14640 | LP52_19700 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.802 |
KIH98166.1 | KIH98339.1 | LP52_14640 | LP52_13715 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.798 |
KIH98166.1 | KIH99296.1 | LP52_14640 | LP52_07925 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.810 |
KIH98166.1 | KII00414.1 | LP52_14640 | LP52_00840 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.713 |
KIH98166.1 | dapF | LP52_14640 | LP52_12785 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.612 |