| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KIH96377.1 | KIH96399.1 | LP52_25385 | LP52_25250 | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.853 |
| KIH96377.1 | KIH97119.1 | LP52_25385 | LP52_20570 | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
| KIH96377.1 | KIH97120.1 | LP52_25385 | LP52_20575 | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
| KIH96377.1 | KIH97251.1 | LP52_25385 | LP52_19950 | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.833 |
| KIH96377.1 | KIH97798.1 | LP52_25385 | LP52_17280 | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.939 |
| KIH96377.1 | KIH97799.1 | LP52_25385 | LP52_17285 | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.885 |
| KIH96377.1 | gltA | LP52_25385 | LP52_05695 | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.750 |
| KIH96377.1 | mdh | LP52_25385 | LP52_12230 | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.835 |
| KIH96399.1 | KIH96377.1 | LP52_25250 | LP52_25385 | methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.853 |
| KIH96399.1 | KIH97119.1 | LP52_25250 | LP52_20570 | methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.968 |
| KIH96399.1 | KIH97120.1 | LP52_25250 | LP52_20575 | methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.978 |
| KIH96399.1 | KIH97251.1 | LP52_25250 | LP52_19950 | methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| KIH96399.1 | KIH97255.1 | LP52_25250 | LP52_19975 | methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.977 |
| KIH96399.1 | KIH97259.1 | LP52_25250 | LP52_19995 | methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.998 |
| KIH96399.1 | KIH97798.1 | LP52_25250 | LP52_17280 | methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.855 |
| KIH96399.1 | KIH97799.1 | LP52_25250 | LP52_17285 | methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.795 |
| KIH96399.1 | gltA | LP52_25250 | LP52_05695 | methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.788 |
| KIH96399.1 | mdh | LP52_25250 | LP52_12230 | methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.800 |
| KIH97119.1 | KIH96377.1 | LP52_20570 | LP52_25385 | methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.900 |
| KIH97119.1 | KIH96399.1 | LP52_20570 | LP52_25250 | methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.968 |