STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIH96947.1Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa)    
Predicted Functional Partners:
KII00439.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.991
KIH99929.1
Metal-dependent phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.984
KII00112.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
0.963
KII00438.1
Response regulator receiver protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.946
KIH98194.1
Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.945
KII00440.1
Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.869
ribA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
    
 0.747
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.747
KII00467.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.744
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.737
Your Current Organism:
Streptomonospora alba
NCBI taxonomy Id: 183763
Other names: CCTCC AA 001013, DSM 44588, JCM 12680, S. alba, Streptimonospora albus, Streptomonospora alba Li et al. 2003, Streptomonospora albus, YIM 90003
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