STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APV44842.1RNA polymerase sigma-70 factor, ECF subfamily. (171 aa)    
Predicted Functional Partners:
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.773
APV44843.1
Hypothetical protein.
       0.773
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.755
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.684
topA
DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.585
APV44841.1
Lipid kinase, YegS/Rv2252/BmrU family; KEGG: pms:KNP414_07252 diacylglycerol kinase (ATP).
  
  
 0.539
APV43600.1
Signal transduction histidine kinase.
  
  
 0.500
APV43601.1
PAS domain S-box-containing protein; 'KEGG: mac:MA2294 two-component system, OmpR family, sensor kinase'.
  
  
 0.496
APV44150.1
PAS domain S-box-containing protein.
   
  
 0.442
APV44903.1
PAS domain S-box-containing protein.
   
  
 0.442
Your Current Organism:
Dehalogenimonas formicexedens
NCBI taxonomy Id: 1839801
Other names: D. formicexedens, Dehalogenimonas formicexedens Key et al. 2017, Dehalogenimonas sp. NSZ-14, HAMBI 3672, JCM 19277, VKM B-3058, strain NSZ-14
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.