STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OLS18745.1DNA double-strand break repair Rad50 ATPase; OdinLCB4_00920 NODE_3_length_93594_cov_3.76123_ID_5_50; IPR027417;IPR003395; arCOG00373. (675 aa)    
Predicted Functional Partners:
OLS18744.1
DNA double-strand break repair protein Mre11; OdinLCB4_00910 NODE_3_length_93594_cov_3.76123_ID_5_49; IPR029052;IPR024654; arCOG00397.
 
 0.999
OLS18743.1
Hypothetical protein; OdinLCB4_00900 NODE_3_length_93594_cov_3.76123_ID_5_48; IPR027417;IPR002789; arCOG00280.
 
   
 0.918
fen
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...]
 
 0.823
OLS18742.1
Hypothetical protein; OdinLCB4_00890 NODE_3_length_93594_cov_3.76123_ID_5_47; IPR018977; arCOG00367.
     
 0.775
OLS18746.1
Hypothetical protein; OdinLCB4_00930 NODE_3_length_93594_cov_3.76123_ID_5_51; IPR002725; arCOG02625.
       0.774
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 0.675
pan
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
   
 
 0.673
dpo1
DNA polymerase 1; OdinLCB4_13740 NODE_1_length_1181447_cov_4.38286_ID_1_1030; IPR003587;IPR004042;IPR017964;IPR006172;IPR006141;IPR03093 4;IPR006134;IPR012337;IPR028992;IPR023211;IPR006133;IPR003 586; arCOG15272.
 
 0.627
hisC
Histidinol-phosphate aminotransferase; OdinLCB4_13550 NODE_1_length_1181447_cov_4.38286_ID_1_1011; IPR001917;IPR005861;IPR015421;IPR015422;IPR004839;IPR01542 4; arCOG04273.
   
 
 0.624
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
    
  0.621
Your Current Organism:
Odinarchaeota archaeon
NCBI taxonomy Id: 1841599
Other names: C. Odinarchaeota archaeon LCB_4, Candidatus Odinarchaeota archaeon LCB_4, archaeon Odin LCB_4
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