STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpdA_23',5'-cyclic adenosine monophosphate phosphodiesterase CpdA; OdinLCB4_11750 NODE_1_length_1181447_cov_4.38286_ID_1_836; IPR029052;IPR028661;IPR000979;IPR024654; arCOG01141. (183 aa)    
Predicted Functional Partners:
mutS2
DNA-binding protein MutS2; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
 
     0.799
gcvPA_2
Putative glycine dehydrogenase (decarboxylating) subunit 1; OdinLCB4_11730 NODE_1_length_1181447_cov_4.38286_ID_1_834; IPR020581;IPR020580;IPR015424;IPR015421; arCOG00077.
       0.773
gcvPB
Putative glycine dehydrogenase (decarboxylating) subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
       0.773
OLS17895.1
Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.740
gcvPA_1
Putative glycine dehydrogenase (decarboxylating) subunit 1; OdinLCB4_11720 NODE_1_length_1181447_cov_4.38286_ID_1_833; IPR020580;IPR020581;IPR015424; arCOG00077.
       0.553
OLS17258.1
Putative peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.457
mtrH
Tetrahydromethanopterin S-methyltransferase subunit H; OdinLCB4_06180 NODE_1_length_1181447_cov_4.38286_ID_1_302; IPR011005;IPR023467; arCOG04336.
  
     0.446
yhdG_2
Putative amino acid permease YhdG; OdinLCB4_15250 NODE_1_length_1181447_cov_4.38286_ID_1_1181; IPR002293; arCOG00009.
     
 0.442
h-ras_1
Transforming protein p29 precursor; OdinLCB4_00670 NODE_3_length_93594_cov_3.76123_ID_5_25; IPR003579;IPR001806;IPR027417;IPR020849.
  
     0.436
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
  0.416
Your Current Organism:
Odinarchaeota archaeon
NCBI taxonomy Id: 1841599
Other names: C. Odinarchaeota archaeon LCB_4, Candidatus Odinarchaeota archaeon LCB_4, archaeon Odin LCB_4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.