STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gloALactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (137 aa)    
Predicted Functional Partners:
gloB
Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
 
  
 0.968
AOG21828.1
Metallo-beta-lactamase superfamily protein; [R] COG0491 Zn-dependent hydrolases, including glyoxylases.
  
  
 0.922
BSY15_863
D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein; [HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases.
    
 0.903
AOG21501.1
glyoxalase/Bleomycin resistance /Dioxygenase superfamily protein; [E] COG0346 Lactoylglutathione lyase and related lyases.
     
  0.900
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
  0.825
ilvA-2
Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 0.824
AOG23271.1
Pyridoxal-phosphate dependent enzyme family protein; [E] COG1171 Threonine dehydratase.
   
 0.824
BSY15_932
Pyridoxal-phosphate dependent enzyme family protein; [E] COG1171 Threonine dehydratase.
   
 0.824
ilvA
ilvA_1Cterm: threonine ammonia-lyase; [E] COG1171 Threonine dehydratase.
   
 0.817
AOG22700.1
Putative serine dehydratase domain protein; [E] COG3616 Predicted amino acid aldolase or racemase.
   
 
  0.806
Your Current Organism:
Acidovorax sp. RAC01
NCBI taxonomy Id: 1842533
Other names: A. sp. RAC01
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