OIJ25309.1 protein (Nocardioides luteus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

OIJ25309.1

Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa)

Predicted Functional Partners:

OIJ25713.1

0.487

OIJ25305.1

0.450

OIJ25307.1

0.430

hemL

0.430

Your Current Organism:

Nocardioides luteus

NCBI taxonomy Id: 1844
Other names: ATCC 43052, CCUG 37986, CIP 103450, DSM 43366, IFO 14491, IMET 7830, JCM 3358, KCTC 9575, LMG 16209, LMG:16209, N. luteus, NBRC 14491

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OIJ25305.1	OIJ25307.1	UG56_017975	UG56_017990	Cytochrome C biogenesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.821
OIJ25305.1	OIJ25309.1	UG56_017975	UG56_018000	Cytochrome C biogenesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.450
OIJ25305.1	hemL	UG56_017975	UG56_017995	Cytochrome C biogenesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate-1-semialdehyde-2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.748
OIJ25307.1	OIJ25305.1	UG56_017990	UG56_017975	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cytochrome C biogenesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.821
OIJ25307.1	OIJ25309.1	UG56_017990	UG56_018000	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.430
OIJ25307.1	hemL	UG56_017990	UG56_017995	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate-1-semialdehyde-2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.967
OIJ25309.1	OIJ25305.1	UG56_018000	UG56_017975	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cytochrome C biogenesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.450
OIJ25309.1	OIJ25307.1	UG56_018000	UG56_017990	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.430
OIJ25309.1	OIJ25713.1	UG56_018000	UG56_016145	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.487
OIJ25309.1	hemL	UG56_018000	UG56_017995	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate-1-semialdehyde-2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.430
OIJ25713.1	OIJ25309.1	UG56_016145	UG56_018000	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.487
hemL	OIJ25305.1	UG56_017995	UG56_017975	Glutamate-1-semialdehyde-2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cytochrome C biogenesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.748
hemL	OIJ25307.1	UG56_017995	UG56_017990	Glutamate-1-semialdehyde-2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.967
hemL	OIJ25309.1	UG56_017995	UG56_018000	Glutamate-1-semialdehyde-2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.430

Network Stats

number of nodes:

11

number of edges:

54

average node degree:

9.82

avg. local clustering coefficient:

0.982

expected number of edges:

17

PPI enrichment p-value:

7.62e-13

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003899

DNA-directed 5-3 RNA polymerase activity

3 of 5

1.87

0.98

0.0126

GO:0005515

Protein binding

3 of 11

1.53

0.81

0.0200

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000428

DNA-directed RNA polymerase complex

3 of 5

1.87

1.34

0.0021

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:189

RNA polymerase

3 of 5

1.87

1.11

0.0066

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

pub03020

RNA polymerase

3 of 4

1.97

1.46

0.0013

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-168256

Immune System

2 of 10

1.39

0.73

0.0266

MAP-9635486

Infection with Mycobacterium tuberculosis

3 of 32

1.06

0.61

0.0266

MAP-5663205

Infectious disease

3 of 33

1.05

0.6

0.0266

MAP-1643685

Disease

3 of 34

1.04

0.6

0.0266

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0240

DNA-directed RNA polymerase

3 of 5

1.87

1.21

0.0039

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00028

Tetratricopeptide repeats

2 of 3

1.91

0.79

0.0315

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (20%) [HD]

Permalink

Network

Neighborhood

Textmining

Cooccurrence

Experiments

Coexpression

Databases

Fusion

© STRING Consortium 2024

Credits

Access

Info

About