node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APX71579.1 | APX71580.1 | BTM29_02950 | BTM29_02955 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.788 |
APX71579.1 | dnaA | BTM29_02950 | BTM29_02945 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Chromosomal replication initiation protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.997 |
APX71579.1 | gyrA | BTM29_02950 | BTM29_02970 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.758 |
APX71579.1 | gyrB | BTM29_02950 | BTM29_02965 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase (ATP-hydrolyzing) subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP [...] | 0.907 |
APX71579.1 | recF | BTM29_02950 | BTM29_02960 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA replication/repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.987 |
APX71580.1 | APX71579.1 | BTM29_02955 | BTM29_02950 | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.788 |
APX71580.1 | APX71587.1 | BTM29_02955 | BTM29_02990 | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | 0.427 |
APX71580.1 | APX71698.1 | BTM29_02955 | BTM29_03625 | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Manganese ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.441 |
APX71580.1 | APX71699.1 | BTM29_02955 | BTM29_03630 | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.555 |
APX71580.1 | dnaA | BTM29_02955 | BTM29_02945 | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chromosomal replication initiation protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.627 |
APX71580.1 | gyrA | BTM29_02955 | BTM29_02970 | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.822 |
APX71580.1 | gyrB | BTM29_02955 | BTM29_02965 | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase (ATP-hydrolyzing) subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP [...] | 0.875 |
APX71580.1 | recF | BTM29_02955 | BTM29_02960 | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA replication/repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.931 |
APX71580.1 | rpsF | BTM29_02955 | BTM29_02975 | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.582 |
APX71580.1 | rpsR | BTM29_02955 | BTM29_02985 | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.449 |
APX71587.1 | APX71580.1 | BTM29_02990 | BTM29_02955 | Hypothetical protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.427 |
APX71587.1 | rpsF | BTM29_02990 | BTM29_02975 | Hypothetical protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.540 |
APX71587.1 | rpsR | BTM29_02990 | BTM29_02985 | Hypothetical protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.680 |
APX71698.1 | APX71580.1 | BTM29_03625 | BTM29_02955 | Manganese ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.441 |
APX71698.1 | APX71699.1 | BTM29_03625 | BTM29_03630 | Manganese ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |