STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHK44642.1Glyoxylase I family protein. (171 aa)    
Predicted Functional Partners:
SHK18380.1
(R)-ethylmalonyl-CoA mutase.
    
 0.792
icmF
methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
 
 0.692
SHL42687.1
Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
    
 0.660
SHL14059.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
     
 0.635
SHJ97193.1
Heterodimeric methylmalonyl-CoA mutase large subunit precursor.
    
 0.630
SHJ97211.1
methylmalonyl-CoA mutase.
    
 0.630
SHL49929.1
Acetyl/propionyl-CoA carboxylase, alpha subunit.
  
 
 0.627
SHK09818.1
CDP-4-dehydro-6-deoxyglucose reductase/toluene monooxygenase electron transfer component.
  
 
 0.626
SHL02888.1
L-threonine ammonia-lyase.
   
 
  0.612
nuoI
NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
 0.565
Your Current Organism:
Pseudonocardia thermophila
NCBI taxonomy Id: 1848
Other names: ATCC 19285, DSM 43832, IFO 15559, JCM 3095, NBRC 15559, VKM Ac-896
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