STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHK58428.1Ankyrin repeat-containing protein. (246 aa)    
Predicted Functional Partners:
SHK41409.1
Z1 domain-containing protein.
  
 0.966
rpsC
SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
    
 0.916
arc
Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
    
 0.905
SHK28961.1
Hypothetical protein.
    
 0.905
SHK64726.1
ATP-dependent helicase HrpB.
    
 0.900
SHL19307.1
ATP-dependent helicase HrpA.
    
 0.900
SHK86606.1
Menaquinol-cytochrome c reductase cytochrome b subunit precursor.
    
  0.894
SHJ98146.1
Tetratricopeptide repeat-containing protein.
 
 0.889
SHK84977.1
Carbonic anhydrase.
    
 
 0.889
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
 0.877
Your Current Organism:
Pseudonocardia thermophila
NCBI taxonomy Id: 1848
Other names: ATCC 19285, DSM 43832, IFO 15559, JCM 3095, NBRC 15559, VKM Ac-896
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.