STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHK69803.1Putative hydrolase/uncharacterized protein, coenzyme F420 biosynthesis associated. (358 aa)    
Predicted Functional Partners:
tilS
tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
     
 0.927
SHK69846.1
Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.926
SHK69786.1
D-alanyl-D-alanine carboxypeptidase / D-alanyl-D-alanine-endopeptidase (penicillin-binding protein 4).
  
  
 0.768
SHK23717.1
Protein of unknown function.
 
     0.602
pafA
Proteasome accessory factor A; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.
  
     0.484
SHJ92200.1
ABC-2 type transport system permease protein.
  
     0.470
SHK68947.1
Hypothetical protein.
  
     0.462
SHL28346.1
Hypothetical protein.
  
     0.459
SHJ93585.1
Proteasome accessory factor A.
  
     0.453
SHJ92143.1
Transcriptional regulator.
  
     0.450
Your Current Organism:
Pseudonocardia thermophila
NCBI taxonomy Id: 1848
Other names: ATCC 19285, DSM 43832, IFO 15559, JCM 3095, NBRC 15559, VKM Ac-896
Server load: low (10%) [HD]