STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaE2Error-prone DNA polymerase, DnaE-like; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1100 aa)    
Predicted Functional Partners:
dnaX
DNA polymerase III, tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 0.981
SHL38386.1
DNA polymerase III, delta subunit.
  
 0.981
SHK67637.1
DNA polymerase-3 subunit delta'.
    
 0.975
SHK80056.1
DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...]
    
 0.959
SHL46775.1
DNA polymerase III, beta subunit.
    
 0.959
SHL47196.1
DNA polymerase-3 subunit epsilon.
  
 0.948
SHL40284.1
Hypothetical protein.
 
  
 0.933
SHL40303.1
Protein ImuB.
 
  
 0.924
SHK81287.1
Single-strand binding protein.
 
 
 0.910
SHK94918.1
Single-strand DNA-binding protein.
   
 0.899
Your Current Organism:
Pseudonocardia thermophila
NCBI taxonomy Id: 1848
Other names: ATCC 19285, DSM 43832, IFO 15559, JCM 3095, NBRC 15559, VKM Ac-896
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