STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB82032.1AMP-binding enzyme; KEGG: ahe:Arch_0547 4.2e-152 AMP-dependent synthetase and ligase; K01897 long-chain acyl-CoA synthetase; Psort location: CytoplasmicMembrane, score: 9.96. (637 aa)    
Predicted Functional Partners:
KXB82025.1
AMP-binding enzyme; KEGG: bcv:Bcav_2594 3.1e-134 AMP-dependent synthetase and ligase; K01897 long-chain acyl-CoA synthetase; Psort location: CytoplasmicMembrane, score: 8.78.
  
  
 
0.906
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.771
valS
Anticodon-binding domain protein; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner.
       0.722
rplE
Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
    
   0.715
KXB81191.1
Hypothetical protein; KEGG: cfi:Celf_0920 2.0e-59 AMP-dependent synthetase and ligase; K01911 O-succinylbenzoic acid--CoA ligase; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.705
KXB79290.1
Hypothetical protein; KEGG: mcu:HMPREF0573_10974 9.4e-46 menE; O-succinylbenzoic acid--CoA ligase K01911; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.675
KXB81553.1
AMP-binding enzyme; KEGG: ahe:Arch_1447 1.2e-68 AMP-dependent synthetase and ligase; K00666 fatty-acyl-CoA synthase; Psort location: Cytoplasmic, score: 9.67.
 
0.672
rplR
Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
    
   0.603
KXB82030.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 8.16.
       0.528
KXB80186.1
Glycosyltransferase, group 2 family protein; KEGG: mcu:HMPREF0573_11692 6.2e-65 dolichyl-phosphate beta-D-mannosyltransferase K00721; Psort location: Cytoplasmic, score: 7.50.
  
   
 0.455
Your Current Organism:
Varibaculum cambriense
NCBI taxonomy Id: 184870
Other names: CCUG 44998, CIP 107344, DSM 15806, V. cambriense, Varibaculum cambriense corrig. Hall et al. 2003, Varibaculum cambriensis, strain R12359
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