STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB81663.1Putative membrane-bound hydrogenase 1 large subunit; KEGG: mcu:HMPREF0573_10781 2.7e-293 hupB; hydrogenase K06281; Psort location: CytoplasmicMembrane, score: 8.78; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (580 aa)    
Predicted Functional Partners:
KXB81662.1
Putative hydrogenase-2 small chain; KEGG: mcu:HMPREF0573_10782 4.0e-189 hupA; hydrogenase K06282; Psort location: CytoplasmicMembrane, score: 9.51.
 
 0.999
KXB81664.1
KEGG: rcp:RCAP_rcc00769 1.3e-20 hupC; hydrogenase, cytochrome b subunit K03620; Psort location: CytoplasmicMembrane, score: 10.00.
 
 
 0.999
hybD
KEGG: mcu:HMPREF0573_10779 2.8e-69 hybD; hydrogenase 2 maturation protease K08567; Psort location: Cytoplasmic, score: 7.50.
 
 0.985
hypA
Putative hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
 
 0.912
porG
2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family; KEGG: mcu:HMPREF0573_10718 5.4e-66 porG; pyruvate/ketoisovalerate oxidoreductase subunit gamma K00172; Psort location: Cytoplasmic, score: 7.50.
   
 
 0.838
KXB81010.1
Putative pyruvate ferredoxin oxidoreductase subunit alpha; KEGG: mcu:HMPREF0573_10719 1.2e-166 porA; pyruvate synthase K00169.
   
 
 0.836
hybF
Putative hydrogenase nickel insertion protein HypA; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.835
KXB81011.1
Thiamine pyrophosphate enzyme, TPP binding domain protein; KEGG: mcu:HMPREF0573_10720 9.5e-156 porB; pyruvate synthase K00170; Psort location: Cytoplasmic, score: 7.50.
   
 
 0.834
KXB81661.1
Hydrogenase accessory protein HypB; KEGG: hdn:Hden_2088 7.2e-07 LAO/AO transporter ATPase; K07588 LAO/AO transport system kinase; Psort location: Cytoplasmic, score: 9.97.
 
   
 0.763
KXB81659.1
Carbamoyltransferase HypF; KEGG: mcu:HMPREF0573_10785 0. hydrogenase maturation protein K04656; Psort location: Cytoplasmic, score: 7.50.
 
 
 
 0.714
Your Current Organism:
Varibaculum cambriense
NCBI taxonomy Id: 184870
Other names: CCUG 44998, CIP 107344, DSM 15806, V. cambriense, Varibaculum cambriense corrig. Hall et al. 2003, Varibaculum cambriensis, strain R12359
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.