STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rphtRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (244 aa)    
Predicted Functional Partners:
KXB81500.1
Putative ribonuclease D; KEGG: tcu:Tcur_1761 1.6e-66 3'-5' exonuclease; K03684 ribonuclease D; Psort location: Cytoplasmic, score: 9.97.
   
 0.999
KXB81529.1
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
 
  0.993
KXB80037.1
KEGG: fal:FRAAL1781 1.1e-193 rpsA; 30S ribosomal protein S1 K02945; Psort location: Cytoplasmic, score: 9.97.
   
  0.981
KXB80573.1
Hydrolase, NUDIX family; KEGG: jde:Jden_1133 3.7e-44 NUDIX hydrolase; K01515 ADP-ribose pyrophosphatase; Psort location: CytoplasmicMembrane, score: 8.16.
    
 0.978
rpsD
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
  0.971
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
  
  0.960
KXB81176.1
KEGG: ske:Sked_18990 4.6e-140 ATP-dependent helicase HrpB; K03579 ATP-dependent helicase HrpB; Psort location: Cytoplasmic, score: 7.50.
    
  0.883
KXB80663.1
KEGG: bcv:Bcav_0228 8.4e-283 ATP-dependent helicase HrpA; K03578 ATP-dependent helicase HrpA; Psort location: Cytoplasmic, score: 7.50.
    
  0.883
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
    
 
 0.882
KXB81859.1
DEAD/DEAH box helicase; KEGG: krh:KRH_08450 1.5e-157 putative DEAD-box RNA helicase; Psort location: Cytoplasmic, score: 9.97.
    
 0.859
Your Current Organism:
Varibaculum cambriense
NCBI taxonomy Id: 184870
Other names: CCUG 44998, CIP 107344, DSM 15806, V. cambriense, Varibaculum cambriense corrig. Hall et al. 2003, Varibaculum cambriensis, strain R12359
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