STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (338 aa)    
Predicted Functional Partners:
lipB
Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
 
 0.999
KXB79995.1
Dihydrolipoyl dehydrogenase; KEGG: jde:Jden_1475 9.7e-163 dihydrolipoamide dehydrogenase; K00382 dihydrolipoamide dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
   
 0.624
KXB79996.1
KEGG: sbh:SBI_07789 1.2e-164 sucB; putative dihydrolipoamide S-succinyltransferase; K00658 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase); Psort location: Cytoplasmic, score: 9.67.
 
  
 0.621
folE
KEGG: shi:Shel_24880 3.3e-59 GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 7.50.
     
 0.611
metXA
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
       0.598
KXB82078.1
KEGG: cfi:Celf_2655 0. 2-oxoglutarate dehydrogenase, E1 subunit; K00164 2-oxoglutarate dehydrogenase E1 component; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.586
KXB81093.1
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
  
 
 0.574
KXB81559.1
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; KEGG: jde:Jden_2111 2.6e-137 O-acetylhomoserine/O-acetylserine sulfhydrylase K01740; Psort location: Cytoplasmic, score: 9.97.
       0.508
obg
Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
 
      0.427
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.419
Your Current Organism:
Varibaculum cambriense
NCBI taxonomy Id: 184870
Other names: CCUG 44998, CIP 107344, DSM 15806, V. cambriense, Varibaculum cambriense corrig. Hall et al. 2003, Varibaculum cambriensis, strain R12359
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