STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menBNaphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. (363 aa)    
Predicted Functional Partners:
menD
Putative 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
  
 0.977
KXB79238.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.964
KXB81191.1
Hypothetical protein; KEGG: cfi:Celf_0920 2.0e-59 AMP-dependent synthetase and ligase; K01911 O-succinylbenzoic acid--CoA ligase; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.946
KXB81197.1
KEGG: bcv:Bcav_3233 1.2e-54 isochorismate synthase; K02552 menaquinone-specific isochorismate synthase; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.915
KXB79290.1
Hypothetical protein; KEGG: mcu:HMPREF0573_10974 9.4e-46 menE; O-succinylbenzoic acid--CoA ligase K01911; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.908
menC
Putative o-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
 
   
 0.898
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
 
   
 0.866
KXB81553.1
AMP-binding enzyme; KEGG: ahe:Arch_1447 1.2e-68 AMP-dependent synthetase and ligase; K00666 fatty-acyl-CoA synthase; Psort location: Cytoplasmic, score: 9.67.
  
 0.843
KXB81133.1
KEGG: cfi:Celf_2525 1.5e-100 mannose-6-phosphate isomerase, class I K01809; Psort location: Cytoplasmic, score: 7.50.
 
      0.495
ligA
DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
 
    
 0.401
Your Current Organism:
Varibaculum cambriense
NCBI taxonomy Id: 184870
Other names: CCUG 44998, CIP 107344, DSM 15806, V. cambriense, Varibaculum cambriense corrig. Hall et al. 2003, Varibaculum cambriensis, strain R12359
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