STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB80736.1KEGG: ske:Sked_35330 1.6e-91 exodeoxyribonuclease III; K01142 exodeoxyribonuclease III; Psort location: Cytoplasmic, score: 9.97. (263 aa)    
Predicted Functional Partners:
KXB79652.1
KEGG: mcu:HMPREF0573_10170 1.3e-71 putative exodeoxyribonuclease III; K01142 exodeoxyribonuclease III; Psort location: Cytoplasmic, score: 9.97.
  
  
 
0.938
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.937
KXB79374.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.928
ung
uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
   
 0.866
KXB81178.1
Cytidine and deoxycytidylate deaminase zinc-binding region; KEGG: fra:Francci3_0280 3.8e-39 tRNA-adenosine deaminase K01485; Psort location: Cytoplasmic, score: 7.50.
   
 
 0.773
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
    0.690
KXB80043.1
Pseudouridylate synthase; KEGG: cga:Celgi_1657 4.5e-62 pseudouridine synthase; K06178 23S rRNA pseudouridine2605 synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the pseudouridine synthase RsuA family.
  
    0.686
KXB80739.1
RNA methyltransferase, TrmH family; KEGG: krh:KRH_01920 1.7e-62 RNA methyltransferase; Psort location: CytoplasmicMembrane, score: 8.16.
 
     0.650
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
      0.596
KXB80738.1
Oxidoreductase, short chain dehydrogenase/reductase family protein; KEGG: rha:RHA1_ro05517 4.2e-27 dehydrogenase K07124; Psort location: Cytoplasmic, score: 9.67; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.549
Your Current Organism:
Varibaculum cambriense
NCBI taxonomy Id: 184870
Other names: CCUG 44998, CIP 107344, DSM 15806, V. cambriense, Varibaculum cambriense corrig. Hall et al. 2003, Varibaculum cambriensis, strain R12359
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.