STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB80525.13-deoxy-7-phosphoheptulonate synthase; KEGG: cfi:Celf_2170 2.6e-162 phospho-2-dehydro-3-deoxyheptonate aldolase K01626; Psort location: Cytoplasmic, score: 7.50; Belongs to the class-II DAHP synthase family. (468 aa)    
Predicted Functional Partners:
KXB82033.1
Chorismate mutase; KEGG: bcv:Bcav_2595 4.0e-31 chorismate mutase; K04092 chorismate mutase; Psort location: Cytoplasmic, score: 7.50.
    
 0.996
KXB80166.1
KEGG: xce:Xcel_1695 7.7e-99 3-dehydroquinate synthase K01735; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.989
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
    
 0.827
KXB80195.1
Transketolase; KEGG: cmi:CMM_1734 1.1e-230 tktA; transketolase K00615; Psort location: Cytoplasmic, score: 7.50; Belongs to the transketolase family.
     
 0.770
pfp
Pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
       0.566
KXB82016.1
KEGG: iva:Isova_1625 2.0e-52 shikimate dehydrogenase; K00014 shikimate dehydrogenase; Belongs to the shikimate dehydrogenase family.
    
 0.534
KXB80523.1
Acyltransferase; KEGG: jde:Jden_1439 1.7e-94 phospholipid/glycerol acyltransferase; K00655 1-acyl-sn-glycerol-3-phosphate acyltransferase; Psort location: CytoplasmicMembrane, score: 8.16.
       0.454
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
     
 0.414
Your Current Organism:
Varibaculum cambriense
NCBI taxonomy Id: 184870
Other names: CCUG 44998, CIP 107344, DSM 15806, V. cambriense, Varibaculum cambriense corrig. Hall et al. 2003, Varibaculum cambriensis, strain R12359
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