STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB80549.1KEGG: eci:UTI89_C3737 8.9e-18 zntR; zinc-responsive transcriptional regulator K13638; Psort location: Cytoplasmic, score: 7.50. (130 aa)    
Predicted Functional Partners:
KXB80548.1
mercury(II) reductase; KEGG: sag:SAG1254 2.1e-279 merA-1; mercuric reductase; K00520 mercuric reductase; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.950
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
   0.729
KXB80730.1
DnaJ domain protein; KEGG: apb:SAR116_1614 5.7e-39 DnaJ family molecular chaperone K03686; Psort location: Cytoplasmic, score: 9.67.
  
   0.729
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.709
sigA
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.667
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.649
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.649
KXB79232.1
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.649
KXB82152.1
KEGG: iva:Isova_2736 9.3e-110 DNA polymerase III subunits gamma and tau; K02343 DNA polymerase III subunit gamma/tau; Psort location: CytoplasmicMembrane, score: 8.78.
    
  0.485
KXB80973.1
KEGG: cfl:Cfla_0576 6.2e-97 DNA polymerase III, delta prime subunit K02341; Psort location: Cytoplasmic, score: 9.97.
    
  0.485
Your Current Organism:
Varibaculum cambriense
NCBI taxonomy Id: 184870
Other names: CCUG 44998, CIP 107344, DSM 15806, V. cambriense, Varibaculum cambriense corrig. Hall et al. 2003, Varibaculum cambriensis, strain R12359
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