STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrCPutative dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (432 aa)    
Predicted Functional Partners:
KXB82051.1
KEGG: pfr:PFREUD_17440 6.8e-107 pyrB; aspartate carbamoyltransferase K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
 
 0.999
KXB80747.1
KEGG: iva:Isova_1606 1.5e-141 carbamoyl-phosphate synthase small subunit K01956; Psort location: Cytoplasmic, score: 7.50.
  
 0.998
KXB80748.1
KEGG: bcv:Bcav_2038 0. carbamoyl-phosphate synthase large subunit; K01955 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family.
 
 0.998
KXB80511.1
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
 0.997
pyrF
KEGG: ske:Sked_18010 1.6e-75 orotidine 5'-phosphate decarboxylase, subfamily 2; K01591 orotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
 
  
 0.987
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
 
 0.980
KXB80197.1
Xanthine permease; KEGG: apb:SAR116_1372 3.8e-58 xanthine/uracil permease K03458; Psort location: CytoplasmicMembrane, score: 10.00.
  
 
 0.915
KXB81012.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: mcu:HMPREF0573_10721 5.0e-221 gltD; glutamate synthase (NADPH) small subunit; Psort location: Cytoplasmic, score: 9.97.
  
 
  0.835
KXB79237.1
Putative permease; KEGG: hiq:CGSHiGG_01870 7.7e-51 upp; uracil phosphoribosyltransferase K02824; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.757
KXB82016.1
KEGG: iva:Isova_1625 2.0e-52 shikimate dehydrogenase; K00014 shikimate dehydrogenase; Belongs to the shikimate dehydrogenase family.
     
 0.740
Your Current Organism:
Varibaculum cambriense
NCBI taxonomy Id: 184870
Other names: CCUG 44998, CIP 107344, DSM 15806, V. cambriense, Varibaculum cambriense corrig. Hall et al. 2003, Varibaculum cambriensis, strain R12359
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