STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEN44061.1Putative chloride channel protein clcB-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (596 aa)    
Predicted Functional Partners:
guaA
GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP.
  
 
 0.841
CEN43893.1
IMP dehydrogenase (fragment); Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
    
 0.658
ribBA
Riboflavin biosynthesis protein RibBA (Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
  
 
 0.655
rmlB
dTDP-glucose 4,6 dehydratase, NAD(P)-binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
    0.637
purL
Putative phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
     
 0.605
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.567
CEN46830.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
   
 
 0.553
kdsD
Arabinose 5-phosphate isomerase KdsD; Belongs to the SIS family. GutQ/KpsF subfamily.
    
  0.542
CEN45824.1
Uncharacterized transporter yfbS.
  
  
 0.533
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
 0.533
Your Current Organism:
Capnocytophaga canis
NCBI taxonomy Id: 1848903
Other names: C. canis, Capnocytophaga canis Renzi et al. 2016, Capnocytophaga sp. HP20001, Capnocytophaga sp. HP33001, Capnocytophaga sp. HP40001, DSM 101831, LMG 29146, LMG:29146, strain CcD38
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