STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaNDNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (375 aa)    
Predicted Functional Partners:
CEN45897.1
DNA polymerase III subunit alpha (fragment).
 
 0.999
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 0.999
holA
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
 
 0.998
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
 0.993
CEN45145.1
DNA polymerase III subunit delta.
 
 
 0.990
dnaX
DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.990
CEN48841.1
Putative Conserved DNA-directed DNA polymerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 0.984
CEN45366.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
 
 0.968
CEN46323.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
 0.957
CEN44477.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
  
 0.955
Your Current Organism:
Capnocytophaga canis
NCBI taxonomy Id: 1848903
Other names: C. canis, Capnocytophaga canis Renzi et al. 2016, Capnocytophaga sp. HP20001, Capnocytophaga sp. HP33001, Capnocytophaga sp. HP40001, DSM 101831, LMG 29146, LMG:29146, strain CcD38
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