OAO01208.1 protein (Sphingomonadales bacterium EhC05)

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

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[Homology]

Score

OAO01208.1

Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa)

Predicted Functional Partners:

OAO01207.1

0.724

OAO01309.1

0.417

Your Current Organism:

Sphingomonadales bacterium EhC05

NCBI taxonomy Id: 1849171
Other names: S. bacterium EhC05

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OAO01207.1	OAO01208.1	A8B75_15630	A8B75_15635	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.724
OAO01207.1	OAO01309.1	A8B75_15630	A8B75_15625	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.592
OAO01208.1	OAO01207.1	A8B75_15635	A8B75_15630	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.724
OAO01208.1	OAO01309.1	A8B75_15635	A8B75_15625	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.417
OAO01309.1	OAO01207.1	A8B75_15625	A8B75_15630	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.592
OAO01309.1	OAO01208.1	A8B75_15625	A8B75_15635	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.417

Network Stats

number of nodes:

11

number of edges:

53

average node degree:

9.64

avg. local clustering coefficient:

0.968

expected number of edges:

11

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:1905323

Telomerase holoenzyme complex assembly

5 of 7

3.13

5.35

1.50e-10

GO:0007004

Telomere maintenance via telomerase

5 of 20

2.67

4.38

5.01e-09

GO:0045793

Positive regulation of cell size

4 of 18

2.62

3.24

8.12e-07

GO:0051131

Chaperone-mediated protein complex assembly

4 of 21

2.55

3.14

1.17e-06

GO:0009651

Response to salt stress

4 of 29

2.41

2.94

2.26e-06

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0002135

CTP binding

4 of 4

3.27

4.4

1.03e-08

GO:0017098

Sulfonylurea receptor binding

4 of 5

3.18

4.38

1.03e-08

GO:0032564

dATP binding

4 of 6

3.1

4.37

1.03e-08

GO:0002134

UTP binding

4 of 6

3.1

4.37

1.03e-08

GO:0030235

Nitric-oxide synthase regulator activity

4 of 7

3.03

4.35

1.03e-08

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0044294

Dendritic growth cone

4 of 13

2.76

3.63

1.78e-07

GO:0097524

Sperm plasma membrane

4 of 23

2.51

3.32

4.72e-07

GO:0044295

Axonal growth cone

4 of 45

2.22

2.73

3.93e-06

GO:0031526

Brush border membrane

4 of 73

2.01

2.28

1.99e-05

GO:0042470

Melanosome

4 of 92

1.91

2.13

3.04e-05

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:7000

Hsp90 protein, and Hsp90 protein binding

6 of 23

2.69

5.73

9.33e-12

CL:7001

Mixed, incl. Telomerase holoenzyme complex assembly, and FK506 binding

5 of 14

2.83

5.02

3.93e-10

CL:18608

Sulfur-containing amino acid secondary active transmembrane transporter activity, and inositol-1,4-bisphosphate 1-phosphatase activity

2 of 5

2.87

1.36

0.0035

CL:7017

Mixed, incl. CTP binding, and SGS domain

2 of 6

2.8

1.32

0.0041

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-3371511

HSF1 activation

5 of 27

2.54

4.44

2.55e-09

MAP-3371568

Attenuation phase

5 of 29

2.51

4.41

2.55e-09

MAP-3371497

HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand

6 of 72

2.19

4.12

1.88e-09

MAP-3371571

HSF1-dependent transactivation

5 of 48

2.29

3.82

1.81e-08

MAP-399954

Sema3A PAK dependent Axon repulsion

4 of 27

2.44

3.29

4.69e-07

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0044294

Dendritic growth cone

3 of 12

2.67

2.17

9.97e-05

GOCC:0030426

Growth cone

4 of 141

1.73

1.54

0.00048

GOCC:0101031

Chaperone complex

2 of 34

2.04

0.72

0.0449

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0346

Stress response

5 of 29

2.51

4.49

1.71e-09

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00183

Hsp90 protein

5 of 6

3.19

5.9

1.57e-11

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00387

Histidine kinase-like ATPases

3 of 15

2.57

2.23

7.18e-05

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