STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (562 aa)    
Predicted Functional Partners:
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.973
NifJ
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
  
 
 0.972
SCZ76810.1
Branched-chain amino acid aminotransferase.
  
 0.969
SCZ81281.1
3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Belongs to the LeuD family.
  
 
 0.962
IlvN
Acetolactate synthase, small subunit.
 
 
 0.925
SCZ80768.1
acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.921
PflB
Formate C-acetyltransferase.
     
 0.900
SCZ80223.1
Malate dehydrogenase (oxaloacetate-decarboxylating).
   
 
 0.825
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 
 0.817
SCZ81283.1
3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Belongs to the LeuD family.
  
 
 0.811
Your Current Organism:
Pseudobutyrivibrio xylanivorans
NCBI taxonomy Id: 185007
Other names: ATCC BAA-455, DSM 14809, P. xylanivorans, Pseudobutyrivibrio xylanivorans Kopecny et al. 2003, Pseudobutyrivibrio xylanovorans, strain Mz 5
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