STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TB927.1.1120Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family. (369 aa)    
Predicted Functional Partners:
Tb10.70.4720
Importin beta-1 subunit, putative.
    
   0.984
Tb927.7.270
Ribosome biogenesis protein, putative.
   
   0.806
Tb927.3.2470
Pumilio/PUF RNA binding protein 8, putative.
   
 
 0.804
Tb11.01.7680
RNA-binding protein, putative.
   
   0.799
Tb927.8.4450
RNA-binding protein, putative.
   
   0.797
Tb10.61.1990
Ribosome biogenesis protein, putative.
   
   0.789
SIR2rp3
NAD-dependent protein deacylase SIR2rp3; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo; Belongs to the sirtuin family. Class III subfamily.
    
 0.789
Tb927.5.1560
ATP-dependent DEAD/H RNA helicase, putative.
   
 
 0.788
Tb11.01.2630
Uncharacterized protein; Belongs to the NOB1 family.
   
  
 0.787
TB927.1.2670
Axoneme central apparatus protein, putative importin alpha-1 subunit, putative.
    
   0.781
Your Current Organism:
Trypanosoma brucei
NCBI taxonomy Id: 185431
Other names: T. brucei brucei TREU927, Trypanosoma brucei TREU927, Trypanosoma brucei brucei TREU927, Trypanosoma brucei brucei strain 927/4 GUTat10.1, Trypanosoma brucei strain TREU927
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.