STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tb927.7.1110Asparagine synthetase a, putative. (351 aa)    
Predicted Functional Partners:
Tb927.5.3820
Aspartate carbamoyltransferase, putative; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
     
 0.924
Tb11.02.2740
Aspartate aminotransferase, mitochondrial.
     
 0.903
Tb11.02.1120
Adenylosuccinate synthetase; Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
    
  0.903
Tb10.70.3710
Aspartate aminotransferase.
     
 0.903
Tb927.3.4060
Asparagine synthetase domain-containing protein.
  
  
 0.842
Tb927.5.3800
Glutamine hydrolysing (Not ammonia-dependent) carbomoyl phosphate synthase, putative.
      
 0.759
Tb927.7.2100
GMP synthase, putative.
      
 0.599
Tb927.3.1360
Cytosine-specific DNA methylase, putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
      
 0.591
Tb927.7.3770
ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to all [...]
     
 0.578
Tb927.7.6270
Peptidase T, putative.
     
 0.577
Your Current Organism:
Trypanosoma brucei
NCBI taxonomy Id: 185431
Other names: T. brucei brucei TREU927, Trypanosoma brucei TREU927, Trypanosoma brucei brucei TREU927, Trypanosoma brucei brucei strain 927/4 GUTat10.1, Trypanosoma brucei strain TREU927
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