STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tb927.2.4590Branched-chain amino acid aminotransferase, putative. (367 aa)    
Predicted Functional Partners:
Tb10.70.2900
Branched-chain alpha-keto acid dehydrogenase e1-beta subunit, putative.
  
 0.936
Tb10.70.7550
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.932
Tb927.6.4430
Homoserine kinase, putative.
  
 
 0.907
Tb10.389.1360
Gamma-glutamylcysteine synthetase.
     
 0.900
Tb927.2.4610
Branched-chain amino acid aminotransferase, putative.
  
  
 
0.900
Tb927.5.4330
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 
 0.796
Tb927.4.2700
Hydroxymethylglutaryl-CoA lyase, putative.
  
 
 0.792
Tb927.7.5480
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
  
  
 0.710
Tb11.01.1120
Phosphonopyruvate decarboxylase-like protein, putative.
  
 
 0.705
Tb927.7.4390
Threonine synthase, putative.
  
 
 0.612
Your Current Organism:
Trypanosoma brucei
NCBI taxonomy Id: 185431
Other names: T. brucei brucei TREU927, Trypanosoma brucei TREU927, Trypanosoma brucei brucei TREU927, Trypanosoma brucei brucei strain 927/4 GUTat10.1, Trypanosoma brucei strain TREU927
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