STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFG33102.13-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (463 aa)    
Predicted Functional Partners:
SFG33123.1
3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 0.999
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 0.999
SFG33142.1
D-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 
 0.997
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
 
 0.991
SFF94296.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
  
 0.928
SFF91255.1
Aspartate kinase.
  
  
 0.667
SFG36555.1
2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).
  
 
  0.644
SFF90726.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.609
SFF85607.1
2-oxoglutarate ferredoxin oxidoreductase subunit beta.
   
 
  0.587
SFG10167.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
    
 0.586
Your Current Organism:
Prevotella sp. KH2C16
NCBI taxonomy Id: 1855325
Other names: P. sp. KH2C16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.