STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEC46464.1Predicted oxidoreductase. (330 aa)    
Predicted Functional Partners:
SEC46520.1
Glucose/arabinose dehydrogenase, beta-propeller fold.
       0.801
SEC46362.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein.
       0.686
SEC46415.1
Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
    0.684
SEC46305.1
Acetolactate synthase, large subunit.
  
    0.652
SEE04362.1
Glycerol uptake facilitator protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
   0.475
SEE06957.1
Aquaporin Z; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
   0.475
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.468
SEC08082.1
Aldo/keto reductase.
 
 
0.467
SEE38081.1
2,5-diketo-D-gluconate reductase A.
 
 
0.464
SEB98694.1
Aldo/keto reductase.
 
 
0.459
Your Current Organism:
Streptomyces sp. 21311
NCBI taxonomy Id: 1855346
Other names: S. sp. 2131.1, Streptomyces sp. 2131.1
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