STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEC55802.1Hypothetical protein. (230 aa)    
Predicted Functional Partners:
SED39919.1
5'-methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage.
  
 
 0.872
SEC55867.1
DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain.
       0.744
SEC55914.1
HAMP domain-containing protein.
       0.744
SED63166.1
Agmatinase; Belongs to the arginase family.
  
 
 0.687
lon
ATP-dependent Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
       0.660
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
 
  
  0.628
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.618
SEB85093.1
Diaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
 0.585
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
 0.585
SEC56010.1
2-oxoglutarate dehydrogenase E1 component.
     
 0.584
Your Current Organism:
Streptomyces sp. 21311
NCBI taxonomy Id: 1855346
Other names: S. sp. 2131.1, Streptomyces sp. 2131.1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.