STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SED92567.1Glycerophosphoryl diester phosphodiesterase. (318 aa)    
Predicted Functional Partners:
SEC38237.1
Glycerophosphoryl diester phosphodiesterase.
  
  
0.917
SED08872.1
Glycerophosphoryl diester phosphodiesterase.
  
  
 
0.917
SEE13769.1
Glycerophosphoryl diester phosphodiesterase.
  
  
 
0.916
SEC80062.1
Glycerol-3-phosphate dehydrogenase.
 
 0.912
SEE04273.1
Glycerol-3-phosphate dehydrogenase.
 
 0.902
SEE08584.1
Glycerophosphoryl diester phosphodiesterase.
  
  
 
0.891
SED92529.1
methylated-DNA-[protein]-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
 
     0.866
SED92609.1
MHYT domain-containing protein, NO-binding membrane sensor.
       0.766
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.735
SEB88031.1
L-lactate dehydrogenase complex protein LldE.
   
 
  0.689
Your Current Organism:
Streptomyces sp. 21311
NCBI taxonomy Id: 1855346
Other names: S. sp. 2131.1, Streptomyces sp. 2131.1
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