STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEE65527.1Predicted nucleic-acid-binding protein, contains Zn-ribbon domain. (201 aa)    
Predicted Functional Partners:
SED40206.1
DNA polymerase III beta subunit, C-terminal domain.
  
 
 0.985
SED36271.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.964
SEC37406.1
D-sedoheptulose 7-phosphate isomerase.
    
 
 0.768
SED10476.1
Protein of unknown function.
   
 
 0.747
SED18462.1
Protein of unknown function.
   
 
 0.747
SED26162.1
AAA domain-containing protein.
   
 
 0.747
SED35201.1
Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
   
 
 0.747
SEC80370.1
Glutamate synthase (NADH) large subunit.
     
 0.696
SED86310.1
Signal transduction histidine kinase.
     
 0.684
recF
DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.
  
  
 0.645
Your Current Organism:
Streptomyces sp. 22311
NCBI taxonomy Id: 1855347
Other names: S. sp. 2231.1, Streptomyces sp. 2231.1
Server load: low (28%) [HD]