STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alsDAlpha-acetolactate decarboxylase; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern; Belongs to the alpha-acetolactate decarboxylase family. (233 aa)    
Predicted Functional Partners:
alsS
Acetolactate synthase; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern; Belongs to the TPP enzyme family.
 
 
 0.997
budC
Diacetyl reductase [(S)-acetoin forming]; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern.
     
 0.901
ydaP
Putative thiamine pyrophosphate-containing protein YdaP; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern; Belongs to the TPP enzyme family.
 
  
 0.677
ipdC
Indole-3-pyruvate decarboxylase; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern.
  
     0.467
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 0.454
sarZ_1
HTH-type transcriptional regulator SarZ; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern.
   
    0.418
sarZ_2
HTH-type transcriptional regulator SarZ; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern.
   
    0.418
mgrA
HTH-type transcriptional regulator MgrA; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern.
   
    0.418
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
      0.406
Your Current Organism:
Macrococcus canis
NCBI taxonomy Id: 1855823
Other names: CCM 8748, CCOS 969, CCOS:969, CCUG 68920, DSM 101690, M. canis, Macrococcus canis Gobeli Brawand et al. 2017, Macrococcus sp. KM45013, strain KM 45013
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