STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lrgAAntiholin-like protein LrgA; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern. (141 aa)    
Predicted Functional Partners:
lrgB
Antiholin-like protein LrgB; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily.
  
 0.996
lytR_1
Sensory transduction protein LytR; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern.
   
 0.963
yohK
Inner membrane protein YohK; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern.
 
  
 0.943
ypdA
Sensor histidine kinase YpdA; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern.
 
   
 0.886
ARQ06116.1
Holin-like protein; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern.
  
   
 0.746
ARQ05891.1
FtsX-like permease family protein; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern.
       0.480
hrtA_2
Putative hemin import ATP-binding protein HrtA; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern.
       0.471
Your Current Organism:
Macrococcus canis
NCBI taxonomy Id: 1855823
Other names: CCM 8748, CCOS 969, CCOS:969, CCUG 68920, DSM 101690, M. canis, Macrococcus canis Gobeli Brawand et al. 2017, Macrococcus sp. KM45013, strain KM 45013
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