STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yvyDPutative sigma-54 modulation protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (186 aa)    
Predicted Functional Partners:
rpmC
50S ribosomal protein L29; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern; Belongs to the universal ribosomal protein uL29 family.
  
 
 
 0.934
rpsI
30S ribosomal protein S9; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern; Belongs to the universal ribosomal protein uS9 family.
   
 
 0.918
rpmA
50S ribosomal protein L27; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern; Belongs to the bacterial ribosomal protein bL27 family.
   
 
 0.918
rpmH
50S ribosomal protein L34; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern; Belongs to the bacterial ribosomal protein bL34 family.
   
 
 0.918
rplI
50S ribosomal protein L9; Binds to the 23S rRNA.
  
   0.914
rpsP
30S ribosomal protein S16; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern; Belongs to the bacterial ribosomal protein bS16 family.
    
 
 0.914
rpsE
30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
    
 
 0.913
rplO
50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
 
 0.913
rpsL
30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
    
 
 0.910
rpsD
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
 
 0.909
Your Current Organism:
Macrococcus canis
NCBI taxonomy Id: 1855823
Other names: CCM 8748, CCOS 969, CCOS:969, CCUG 68920, DSM 101690, M. canis, Macrococcus canis Gobeli Brawand et al. 2017, Macrococcus sp. KM45013, strain KM 45013
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