STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sdhBL-serine dehydratase, beta chain; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern; Belongs to the iron-sulfur dependent L-serine dehydratase family. (221 aa)    
Predicted Functional Partners:
sdhA
L-serine dehydratase, alpha chain; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern; Belongs to the iron-sulfur dependent L-serine dehydratase family.
 
 0.999
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.952
cysE
Serine acetyltransferase; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern.
     
 0.907
mccB
Cystathionine gamma-lyase; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern.
   
 
 0.828
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
 
 0.826
hom
Homoserine dehydrogenase; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern.
   
 
  0.815
metA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
     
 0.807
ARQ07487.1
Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily protein; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern.
   
 
  0.801
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
  
    0.779
ARQ06697.1
Sortase family protein; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern.
 
     0.757
Your Current Organism:
Macrococcus canis
NCBI taxonomy Id: 1855823
Other names: CCM 8748, CCOS 969, CCOS:969, CCUG 68920, DSM 101690, M. canis, Macrococcus canis Gobeli Brawand et al. 2017, Macrococcus sp. KM45013, strain KM 45013
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.