STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
korB2-oxoglutarate oxidoreductase subunit KorB; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern. (287 aa)    
Predicted Functional Partners:
korA
2-oxoglutarate oxidoreductase subunit KorA; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern.
 0.999
pyk
Pyruvate kinase; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern; Belongs to the pyruvate kinase family.
  
 0.943
pta
Phosphate acetyltransferase; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern.
   
 0.942
sucC
Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.936
sucD
Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.931
pflB
Formate acetyltransferase; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern.
    
 0.928
ldhA
L-lactate dehydrogenase 1; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 
 0.926
ldh_1
L-lactate dehydrogenase; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern; Belongs to the LDH/MDH superfamily.
  
 
 0.926
ppdK
Pyruvate, phosphate dikinase; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern.
    
 0.926
citZ
Citrate synthase 2; Bacteria and source DNA available from Institute of Veterinary Bacteriology, University Bern; Belongs to the citrate synthase family.
   
 
 0.923
Your Current Organism:
Macrococcus canis
NCBI taxonomy Id: 1855823
Other names: CCM 8748, CCOS 969, CCOS:969, CCUG 68920, DSM 101690, M. canis, Macrococcus canis Gobeli Brawand et al. 2017, Macrococcus sp. KM45013, strain KM 45013
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