LuPra_00217 protein (Luteitalea pratensis) - STRING interaction network

Nodes:

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second shell of interactors

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Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

LuPra_00217

Translocation protein TolB. (533 aa)

Predicted Functional Partners:

LuPra_00216

0.852

LuPra_01858

0.671

LuPra_00856

0.632

LuPra_02556

0.601

LuPra_01251

0.595

LuPra_03713

0.594

LuPra_02091

0.575

LuPra_02434

0.572

LuPra_01836

0.563

LuPra_06300

0.553

Your Current Organism:

Luteitalea pratensis

NCBI taxonomy Id: 1855912
Other names: Acidobacteria bacterium DSM 100886, Acidobacteria bacterium HEG_-6_39, DSM 100886, KCTC 52215, L. pratensis, Luteitalea pratensis Vieira et al. 2017, strain HEG_-6_39

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
LuPra_00216	LuPra_00217	Cupin_2 domain-containing protein.	Translocation protein TolB.	0.852
LuPra_00216	LuPra_01858	Cupin_2 domain-containing protein.	Uncharacterized protein.	0.427
LuPra_00217	LuPra_00216	Translocation protein TolB.	Cupin_2 domain-containing protein.	0.852
LuPra_00217	LuPra_00856	Translocation protein TolB.	Translocation protein TolB.	0.632
LuPra_00217	LuPra_01251	Translocation protein TolB.	Putative metal-dependent hydrolase of the TIM-barrel fold protein.	0.595
LuPra_00217	LuPra_01836	Translocation protein TolB.	Putative metal-dependent hydrolase of the TIM-barrel fold protein.	0.563
LuPra_00217	LuPra_01858	Translocation protein TolB.	Uncharacterized protein.	0.671
LuPra_00217	LuPra_02091	Translocation protein TolB.	Putative metal-dependent hydrolase of the TIM-barrel fold protein.	0.575
LuPra_00217	LuPra_02434	Translocation protein TolB.	Translocation protein TolB.	0.572
LuPra_00217	LuPra_02556	Translocation protein TolB.	Bacterial alpha-L-rhamnosidase.	0.601
LuPra_00217	LuPra_03713	Translocation protein TolB.	Uncharacterized protein.	0.594
LuPra_00217	LuPra_06300	Translocation protein TolB.	Putative metal-dependent hydrolase of the TIM-barrel fold protein.	0.553
LuPra_00856	LuPra_00217	Translocation protein TolB.	Translocation protein TolB.	0.632
LuPra_00856	LuPra_02434	Translocation protein TolB.	Translocation protein TolB.	0.766
LuPra_01251	LuPra_00217	Putative metal-dependent hydrolase of the TIM-barrel fold protein.	Translocation protein TolB.	0.595
LuPra_01836	LuPra_00217	Putative metal-dependent hydrolase of the TIM-barrel fold protein.	Translocation protein TolB.	0.563
LuPra_01858	LuPra_00216	Uncharacterized protein.	Cupin_2 domain-containing protein.	0.427
LuPra_01858	LuPra_00217	Uncharacterized protein.	Translocation protein TolB.	0.671
LuPra_01858	LuPra_02556	Uncharacterized protein.	Bacterial alpha-L-rhamnosidase.	0.598
LuPra_01858	LuPra_03713	Uncharacterized protein.	Uncharacterized protein.	0.410

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

27

average node degree:

4.91

avg. local clustering coefficient:

0.786

expected number of edges:

34

PPI enrichment p-value:

0.914

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006351

Transcription, DNA-templated

5 of 20

1.87

2.45

3.51e-06

GO:0010467

Gene expression

9 of 208

1.11

1.3

1.46e-06

GO:0009059

Macromolecule biosynthetic process

9 of 232

1.06

1.21

1.88e-06

GO:0031564

Transcription antitermination

2 of 4

2.17

0.98

0.0148

GO:0006353

DNA-templated transcription, termination

2 of 4

2.17

0.98

0.0148

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003899

DNA-directed 5-3 RNA polymerase activity

3 of 5

2.25

1.7

0.00058

GO:0003735

Structural constituent of ribosome

4 of 55

1.33

1.0

0.0035

GO:0003723

RNA binding

5 of 96

1.19

0.98

0.0015

GO:0003676

Nucleic acid binding

9 of 370

0.86

0.78

0.00012

GO:0019843

rRNA binding

3 of 40

1.34

0.7

0.0297

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000428

DNA-directed RNA polymerase complex

3 of 6

2.17

1.8

0.00033

GO:0005840

Ribosome

4 of 59

1.3

1.06

0.0018

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:74

Ribonucleoprotein, and Translation regulator activity

11 of 92

1.55

3.38

1.42e-14

CL:77

Ribosome, and Translation regulator activity

9 of 75

1.55

3.02

1.33e-11

CL:99

Ribosome

5 of 37

1.6

2.03

6.66e-06

CL:84

Ribosome

6 of 62

1.46

1.93

1.80e-06

CL:101

rRNA-binding

3 of 23

1.58

1.16

0.0030

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

con03020

RNA polymerase

3 of 4

2.34

2.07

0.00012

con03010

Ribosome

4 of 53

1.35

1.11

0.0015

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0008023

Transcription elongation factor complex

2 of 2

2.47

0.99

0.0157

GOCC:0000428

DNA-directed RNA polymerase complex

4 of 63

1.27

0.77

0.0157

GOCC:0022627

Cytosolic small ribosomal subunit

2 of 11

1.73

0.76

0.0320

GOCC:0005840

Ribosome

3 of 47

1.27

0.71

0.0238

GOCC:0032991

Protein-containing complex

8 of 534

0.65

0.43

0.0157

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0240

DNA-directed RNA polymerase

3 of 7

2.1

1.84

0.00025

KW-0689

Ribosomal protein

5 of 59

1.4

1.37

0.00023

KW-0889

Transcription antitermination

2 of 3

2.29

1.3

0.0037

KW-0806

Transcription termination

2 of 3

2.29

1.3

0.0037

KW-0548

Nucleotidyltransferase

3 of 33

1.43

1.0

0.0052

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00322

K homology RNA-binding domain

2 of 3

2.29

1.06

0.0110

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