STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (445 aa)    
Predicted Functional Partners:
hpd
4-hydroxyphenylpyruvate dioxygenase.
 
 0.994
LuPra_03284
Fumarylacetoacetase.
  
 0.960
phhA
Phenylalanine-4-hydroxylase.
 
  
 0.921
LuPra_01453
Methylmalonyl-CoA epimerase.
  
 
 0.863
LuPra_05356
Uncharacterized protein.
  
 
 0.861
LuPra_01982
Ureidoglycolate lyase.
  
  
 0.801
LuPra_05473
Ureidoglycolate lyase.
  
  
 0.801
polA_2
DNA polymerase I.
       0.768
pcpB
Pentachlorophenol 4-monooxygenase.
 
  
 0.597
kynU
Kynureninase.
 
  
 0.585
Your Current Organism:
Luteitalea pratensis
NCBI taxonomy Id: 1855912
Other names: Acidobacteria bacterium DSM 100886, Acidobacteria bacterium HEG_-6_39, DSM 100886, KCTC 52215, L. pratensis, Luteitalea pratensis Vieira et al. 2017, strain HEG_-6_39
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