STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
UBA4Adenylyltransferase and sulfurtransferase UBA4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subseque [...] (400 aa)    
Predicted Functional Partners:
M5FWL7_DACPD
Cysteine desulfurase.
   
 0.989
M5FXU5_DACPD
Ubiquitin-related modifier 1; Belongs to the URM1 family.
    
 0.976
M5FUC5_DACPD
Uncharacterized protein.
    
 0.946
M5FQU5_DACPD
Rhodanese-like protein.
   
 0.903
M5FQI1_DACPD
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.
    
 0.884
M5GDT0_DACPD
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.881
M5GFD9_DACPD
Uncharacterized protein.
   
 0.878
M5GBF0_DACPD
Uncharacterized protein.
    
 0.866
M5GFU0_DACPD
Autophagy-related protein 3.
    
 0.866
M5FRD0_DACPD
UBIQUITIN_CONJUGAT_2 domain-containing protein.
  
 0.848
Your Current Organism:
Dacryopinax primogenitus
NCBI taxonomy Id: 1858805
Other names: D. primogenitus, DJM 731, DJM-731 SS1, Dacryopinax primogenitus D. J. McLaughlin & E. G. McLaughlin, 2016, Dacryopinax sp. DJM-731 SS1, Dacryopinax sp. MIN 862738, MIN 929365
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