STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
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[Homology]
Score
M5G9P4_DACPDDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (866 aa)    
Predicted Functional Partners:
M5FZC5_DACPD
P-loop containing nucleoside triphosphate hydrolase protein.
   
 0.998
M5G548_DACPD
Ribonuclease H-like protein.
   
 0.997
M5G9J0_DACPD
DUF1767-domain-containing protein.
    
 0.997
M5G9M6_DACPD
Replication protein A subunit RPA32.
    
 0.966
M5FX88_DACPD
ERCC4 domain-containing protein.
    
 0.928
M5FNI0_DACPD
Uncharacterized protein.
   
 0.923
M5FWA8_DACPD
RecQ_Zn_bind domain-containing protein.
   
 0.923
M5G2K9_DACPD
Uncharacterized protein.
   
 0.923
M5G4R7_DACPD
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
   
 0.923
M5G599_DACPD
Uncharacterized protein.
   
 0.923
Your Current Organism:
Dacryopinax primogenitus
NCBI taxonomy Id: 1858805
Other names: D. primogenitus, DJM 731, DJM-731 SS1, Dacryopinax primogenitus D. J. McLaughlin & E. G. McLaughlin, 2016, Dacryopinax sp. DJM-731 SS1, Dacryopinax sp. MIN 862738, MIN 929365
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.